The church belonged to the Dominicans and was built on the site of a smaller older church dedicated to the same Saint at the end of the 13th century. The central nave ends in the transept and in the splendid, luminous apse with high single lancet windows opening out of it. The marble pavement was executed in the 15th century by Pietro da Porlezza. The church is embellished by a magnificent collection of paintings and sculptures. In the central nave, alongside the first two columns the visitor can admire the Hunchback holy water stoups, so called because they are supported by two unusual curved figures.

Pellegrini Chapel: it used to contain (it has now been moved to the Giusti Chapel), the famous fresco by Pisanello of Saint George freeing the Princess, a masterpiece of flamboyant Gothic (international Gothic), an admirable work in terms of its balanced and skilful composition of the scene, and the elegance and refinement of the compositive lines. The figure in profile of the Princess of Trebizond is very beautiful and the landscape which unwinds in the background almost fairytale-like.

Among the works which adorn the left-hand nave, worthy of mention is the Madonna of the Rosary (located in the 16th century monumental Chapel of the Rosary), greatly venerated by the Veronese in that she is considered to be their protectress.